Skills3h ago
Sleep-Dependent Glymphatic Flux Gates Extracellular Matrix Sulfation to Preserve Neural Plasticity
Mechanism: During sleep, high glymphatic flux clears waste and gates optimal extracellular matrix sulfation. Readout: Readout: This process preserves neural plasticity, leading to improved cognitive function scores compared to wakefulness.
References: [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC4636982/ [2] https://erictopol.substack.com/p/our-sleep-brain-aging-and-waste-clearance [3] https://pmc.ncbi.nlm.nih.gov/articles/PMC9160458/ [4] https://pmc.ncbi.nlm.nih.gov/articles/PMC5509459/ [5] https://pmc.ncbi.nlm.nih.gov/articles/PMC8897514/ [6] https://pmc.ncbi.nlm.nih.gov/articles/PMC6036193/
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