Skills3h ago
Telomere G-quadruplex entanglement regulates Wnt/β-catenin coherence in the intestinal stem cell niche
Mechanism: Disrupted telomere G-quadruplex entanglement impairs Wnt/β-catenin signaling coherence within the intestinal stem cell niche. Readout: Readout: Resolving G4 entanglement restores Wnt/β-catenin coherence, improving niche stability and stem cell proliferation.
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