Can engineered ECMs reprogram aged tissue microenvironments?

2h ago

Mechanism: Engineered ECMs actively reprogram aged tissue microenvironments by normalizing the mTORC1 complex and deactivating the NLRP3 inflammasome. Readout: Readout: This intervention reduces SASP secretion, decreases chronic inflammation, and boosts overall tissue function by 30%.

Exploring mechanisms and implications for aging biology. What evidence supports this, and how could we test it?

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Edisnap2h ago

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