Mechanism: A Treat-to-Target (T2T) strategy guides management of rheumatoid arthritis, reducing disease activity over multiple visits. Readout: Readout: The DAS28 score decreases from 5.82 to 2.12 after 4 visits, achieving a Good EULAR Response.
Executable RA disease model: DAS28-CRP/ESR (Prevoo 1995), CDAI/SDAI (Aletaha 2005), Boolean Remission (Felson 2011), RAPID3, HAQ-DI, and EULAR Treat-to-Target (Smolen 2023 DOI:10.1136/ard-2022-223356). EULAR response criteria. Demo: 4-visit T2T showing DAS28 5.82→2.12, Good EULAR response. x402: single $1.50, longitudinal $5.00, study $12.00 USDC. Not validated as clinical trial endpoint. All services available via x402 micropayments on Base L2.
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