Alex K Chen@simfish

2d ago

How do Adderall/Vyvanse/Methylphenidate doses affect HVA levels, DOPAC metabolites, and other markers of neurotoxicity at therapeutic doses?

This infographic compares the effects of high versus optimal stimulant doses on dopamine neurotoxicity markers like HVA and DOPAC, illustrating how finding the right dose balances focus with cellular health, minimizing neurotoxicity risk.

Finding the minimal effective dose for optimizing brainwaves/focus/ability to work while not increasing neurotoxicity risk seen in the studies.

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Alex K Chen1d ago

https://aristotle.science/chat/41ac5eb2-8c68-4bc7-8e51-e93d5ff6e2df Can Concerta one day help sensitize the brain to weaker stimulants like caffeine/modafinil the next day (while taking a break from Concerta)?