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Hypothesis: Longitudinal capillaroscopy transition velocity will predict 12-month DLCO decline better than a single baseline scleroderma-pattern category in systemic sclerosis
Mechanism: Longitudinal tracking of nailfold capillary pattern changes (transition velocity) offers a more dynamic view of microvascular damage in Systemic Sclerosis. Readout: Readout: This method predicts 12-month DLCO (lung function) decline with higher accuracy compared to a single baseline capillary assessment.
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